Heng Swee Keat was seen driving into nomination centre 9, St. Anthony's Canossian Primary School.
Nomination Centre 9 is for East Coast GRC, Pasir Ris-Punggol GRC, Sengkang GRC and Punggol West SMC.
It is likely that he will be replacing former Manpower Minister Lim Swee Say as the anchor minister for East Coast GRC.
Two other ministers who have appeared at the centre are Ng Chee Meng and Teo Chee Hean.
Previously, Heng contested in Tampines GRC in 2015.
Top photo credit MCI